Molecular structure elucidation and chemical structure confirmation expertise to determine the atom connectivity and composition of chemical compounds

Elucidation of molecular structure is necessary to identify or confirm the structural identity of a chemical compound during chemical research or product development.

Unknown substances or impurities can be difficult to identify. Chemical structural elucidation of impurities is necessary to support compound regulatory submissions for a number of industrial sectors such as agrichemicals, pharmaceutical and new chemical entity registrations.

We apply our expertise analysis to elucidate the structure of new chemical entities, identify impurities and conduct chemical composition characterization. 

Our experts use mass spectrometry techniques to determine molecular weight and apply tandem MS/MS approaches to provide valuable data in the identification of an unknown molecule. During the process, our Spectroscopy scientists apply techniques such as 1H and 13C Nuclear Magnetic Resonance (NMR) to explore and confirm the connectivity of the atoms in the molecule. Elemental analysis methods such as Inductive coupled plasma spectroscopy  (ICP-OES) effectively help to determine the elements present in the chemical compound in question. Often the combination of information from these multiple techniques can yield a comprehensive picture of the compound structure and therefore confirm identity. Such a process requires the application of the correct methods coupled with a skilled and highly knowledgable approach.

Our experts can also apply a range of techniques including NMR and chromatography approaches to study and confirm optical isomers of chiral molecules.

Structural elucidation techniques include

  • GCMS
  • Nuclear magnetic resonance (NMR) spectroscopy 
  • Mass spectrometry
  • FTIR spectroscopy
  • Elemental Analysis

With Intertek as your partner, you will receive the benefits of expert application of the most accurate methods reinforced by our  expertise. Our global network of chemical analysis laboratories utilise a range of technologies during structural elucidation projects to support the identification and confirmation of molecules. With a team of experts who have acquired many years of experience in a wide range of samples and industry sectors we are able to provide the structural data you require to progress your research or product development programs or complete your regulatory submissions.

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