In Vitro Oral Care Product Laboratory Testing

In vitro oral care product laboratory testing studies for dental hygiene products such as toothpaste, mouthwash, strips, brushes and more to evaluate performance and marketing claims, supporting product development, including stain removal, stain prevention, whitening, gloss, brushing performance, abrasivity, erosion and dentine tubule blockage assessment and the design of bespoke models for your novel products
Why are in vitro oral care product testing studies important?
In vitro laboratory testing for oral care products to determine function, performance and efficacy can help to accelerate product development and support marketing claims. To protect your brand and meet your consumer's expectations, you will need to demonstrate that your novel oral hygiene products perform well and that you can support your marketing claims such as achieving whiter teeth, stain removal, stain prevention, anti-plaque, anti-calculus properties or increased tooth gloss or decreased product abrasivity. The oral care products market is expected to grow significantly, driven by awareness of dental hygiene, and the increasing popularity of personal aesthetics. Innovation continues to bolster this sector with the introduction of novel dental health products, and devices such as remineralising toothpaste, novel whitening treatments or electric/battery supported toothbrushes. Developing accurate, appropriate, and successful claims to describe your product and simultaneously express your brand values is more important than ever to support a successful product launch.
In vivo clinical studies for oral health care products are the gold standard in terms of product assessment, however, these can be rather complex, time-consuming and expensive. Instead, a well-designed in vitro test can often yield the required data much more quickly and at a lower cost. Such studies, whether they are to support early-stage oral health innovations of a product formulation or in support of marketing claims or pack claims, may be rapidly conducted to generate robust data to support the screening of oral care product formulations or designs to target those most promising for your human oral care clinical studies. Data from in vitro testing can enable rigorous assessment supporting product development and advertising claims.
In vitro laboratory testing supporting claims and product development
Our in vitro oral care laboratory team design and conduct evaluation studies for dental care products including tooth paste, toothbrushes, dentifrice products, interproximal devices, floss, mouthwashes, gels and tablets, and all novel oral care products. We support oral care innovations and product developers to accelerate their development timelines, whilst delivering data and insight on product efficacy and performance through oral care product laboratory studies. Our experts have over 20+ years of experience in supporting claim substantiation submissions. Such studies may involve routine and bespoke methodologies in the areas of stain removal, stain prevention, whitening, gloss, brushing performance, abrasivity, erosion and dentine tubule blockage.
- Anti-Stain, Stain Removal, and Tooth Whitening Product Testing
- Anti-plaque and Anti-calculus Testing
- Abrasivity / tissue loss using 2-D probe profilometry
- Artificial brushing machines for cleaning/abrasivity testing
- Cleaning evaluation of toothbrushes, interdental brushes, flosses and tapes
- Enamel erosion by acidic drinks or foods
- Impact of tooth colouration by food, drinks or pharmaceuticals
- Dentinal tubule blockage experiments for sensitivity claims
- Pellicle Cleaning Ratio (PCR) Studies
- Laboratory Remineralisation/Demineralisation Testing
Hard tissue services:
We are proficient at preparing dental hard tissue samples such as enamel blocks (human and bovine) and dentine discs. Our laboratory is equipped with a variety of wafering saws, wire saws, lapping and polishing machines enabling us to produce samples to any desired specification or finish. We can also produce artificial lesions for use in a variety of enamel remineralisation studies.
- Human and bovine hard tissue sample preparation (enamel/dentine) including hydroxyapatite
- Supply of Discs/Blocks of dental restoration materials
- Artificial lesion preparation in enamel samples using acid gels
Bioanalytical and instrumental measurements:
Our laboratories also provide sample analysis in support of your oral care clinical studies (e.g. fluoride, calcium and, other active agents) and can carry out SEM and surface microhardness analysis of in situ hard tissue samples. We are inspected and licensed by the Human Tissue Authority (HTA). Our GCP and GLP compliant bioanalytical laboratories are inspected by the MHRA.
- Surface Microhardness (SMH) evaluation of human/bovine enamel/dentine
- Fluoride/potassium/calcium/zinc analysis of plaque and saliva
- Oral malodour assessment using GC / OralChroma / Halimeters
- Plaque/saliva sample preparation for active agent analysis
- Operation of Periotrons for Gingival Crevicular Fluid Analysis
With over 20 years of experience designing and conducting in vitro oral care studies, we have been a trusted partner for developers and manufacturers of dental care products and oral care products. Our scientists deliver Total Quality Assurance for our customers, enabling them to power ahead safely by offering in vitro method development for bespoke models and screening of oral care products to target those most promising for further product development with rigorous assessment supporting safety, regulatory compliance, and advertising claim support.
Consumer product trial and study services:
Oral Care Research Resources
New White Paper:
Accelerating Oral Care Product Development - Partnership With In Vitro Assessment Experts
FOCUS ON TEETH WHITENING:
Benchmarking Stain Prevention and Stain Removal Agents in Oral Care Products
Quantifying Tooth Whitening in Terms Of X-Shades Whiter
Comparison of The Ability Of Toothpaste Formulations To Remove Surface Stains
CASE STUDY LIBRARY:
Benchmarking Anti-Plaque Agents In Dentifrices And Mouthwashes
The Impact of a Toothpaste pH-Buffering System on Dental Plaque pH
The Effect of Foods, Drinks or Pharmaceuticals on Teeth Colouration
Dentine and Enamel Block Preparation
Efficacy Assessment of Interdental Brushes
Dentine Tubule Occlusion Studies
Measuring Tooth Demineralisation and Remineralisation In Vitro
BROCHURES:
Intertek Oral Care Product In Vitro Development Support Services
WHITE PAPERS:
Evaluation of Toothbrush Performance
Oral Care In Vitro Stain Removal Testing
RECORDED WEBINARS:
In vitro Oral Care Product Testing
Tooth Whitening: In Vitro Laboratory Support Studies
In Vitro Oral Care Product Services
Elm House, Unit A4
Oaklands Office Park
Hooton Road, Hooton
Cheshire, CH66 7NZ
United Kingdom
News
Access our Recorded Webinar: Clinical and In Vitro Support for Tooth Whitening Product Development