Case Study: Comparison of the Ability of Toothpaste Formulations to Remove Surface Stains

Innovation is a core focus for science-led developers of oral care products such as toothpastes. These products must be evaluated for efficacy and performance with a robust, scientific approach. A pellicle cleaning ratio test (PCR) is an in vitro method designed to compare the ability of toothpaste formulations to remove surface stains. The ranking of toothpastes in this test has been shown to compare favourably with the results of controlled clinical trials, hence a PCR test can be considered as reasonably predictive. In this case study, our expert introduces the PCR test approach  and the benefits to developers as a cost-effective route to faster ranking of the cleaning performance of toothpastes.