Considerations when Switching from Current pMDI Propellants to New Lower-GWP Propellants


In this article, Mark Parry, Senior Scientific Director at Intertek, discusses considerations that need to be made when switching from current pressurised metered dose inhaler propellants to new alternatives with lower global warming potential, including formulation, regulatory and analytical standpoints. 

“Whichever propellant is selected, despite the somewhat similar physical properties, reformulation of existing products may not be as simple as a drop-in replacement of the new propellant.” ONdrugDelivery, Issue 145, pp 6–9.

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