Ensuring Oligonucleotide Quality Control Using Ion-pair HPLC with UV and MS Detection for Oligonucleotide Identification, Assay and Impurities

Determination of purity and levels of product related impurities present a fundamental attribute for quality control of oligonucleotide products. Download this Case Study to learn how our scientists apply ion-pair chromatography coupled to mass spectrometry to determine the %purity, the impurity profile and the identity of an oligo product.