Analysis of particulate contamination issues by various methods including microscope, SEM, FTIR, Raman spectroscopy
Identification of particulate contaminants is the first step in the resolution of potentially critical contamination problems which might occur unexpectedly at multiple points along the supply chain for many industries. Once the source is known, however, action can be taken to control and prevent future contamination.
Identification of particulate contaminants requires isolation of the particulate matter followed by comprehensive analysis and identification.
Our experts apply their knowledge and experience to locate the source of the contaminant and eliminate it, or find the source of the problem in the supply chain. We adopt a strategic approach to identify contaminants which includes expertise in sampling and sample preparation, visual / physical examination, chemical identification and cause analysis.
Using microscopy techniques, contaminant particles are imaged and compared to the main population by our experts. Following an initial assessment, analysis can be performed using Energy-dispersive X-ray spectroscopy (EDS, EDX, or XEDS) on isolated particles using Scanning Electron Microscopy (SEM) or vibrational spectroscopy (infra-red or Raman), as appropriate. When the size or shape of the contaminating particles is the issue, image analysis is used to assess and quantify the degree of contamination so that comparisons with other batches or a retained standard can be made.
Examples of contamination in powders
Examples of particulate contaminant problems we have helped to resolve
We offer fast standardized services for identification and characterization of particulate contaminants and impurities
Whether your contamination is embedded in a solid, gel or liquid, is present in a homogeneous or heterogeneous environment, is of organic or inorganic nature or appears as fibres or crystallites, our experts apply the most suitable preparation method for your samples.
Sampling of particles is rarely straightforward and cross-contamination has to be avoided. We can advise on proper sample collection and can suggest appropriate sample packing or can provide the proper packaging material.
Alternatively, our experts can visit your site and take care of sample collection and transport.
We have the capability to fully review analytical results and assess the findings of analytical studies focused on contamination incidents associated with production, engineering and the supply chain. We can provide the guidance you need to define corrective and preventive measures.
Our broad experience in many industries such as the pharmaceutical, medical device, polymer and coating sectors gives us the necessary know-how to effectively identify unknown contaminants. We provide comprehensive characterization and identification of particulate contaminates, ensuring that a highly sensitive and stressful process is dealt with in a streamlined and meaningful manner.
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