Pharmaceutical particle and powder characterisation services to assist understanding of physical properties to optimize formulation and production
Pharmaceutical manufacturing processes and products often involve suspensions and bulk powders. The finished pharmaceutical product may also be used in conjunction with a delivery device.
Particle size will influence physical properties, such as the flowability of a powder, and in turn, will impact processing, blending, tableting, dissolution, delivery and bioavailability. When the pharmaceutical product is delivered via a device such as inhalation technology, device development challenges related to the powder / particle or suspension properties may be experienced. Manufacturing scale up processes may lead to changes in the particle shape and size leading to changes in flowability and ultimately the aerosolisation of the powder.
Our physical characterisation experts employ powder rheology testing and shape analysis to assist understanding of potential issues faced by the developers and manufacturers. Our teams are experienced in device and formulation compatibility assessment with the ability (and technology) to map and characterize device / formulation performance during early stage development in order to address problems related to device development.
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