Dynamic Light Scattering Services

Dynamic light scattering (DLS) services for the measurement of particulate size distribution and for monitoring aggregation of proteins in solution or suspensions

Size and particle size distribution of particulate samples are essential parameters, and their ongoing, accurate monitoring ensures product consistency. High throughput DLS is used by our experts in routine studies of particles in solutions, dispersed systems, and biologics, such as proteins, in solution. The instrument can perform a combination of the three most important parameters for the colloid and polymer chemist and these are particle size analysis, zeta potential measurement and molecular weight measurement.

The instrumentation is qualified to GLP and cGMP standards which means that the data can be used in regulatory projects, pharmaceutical QC or to support product development. Our scientists deploy this technology to assist clients who are developing drug delivery systems or biologic therapeutics and it is extremely relevant to protein stability studies, comparability studies and biopharmaceutical GMP release testing.

Dynamic Light Scattering Measurements Available:

  • Particle Size Analysis
    NIBS technology enables measurements of particles and molecules from 0.6nm to 6 microns.
  • Zeta Potential
    M3-PALS technology enables accurate measurements of zeta potential in aqueous and non-aqueous dispersions.
  • Molecular Weight
    An avalanche-photodiode detector and fibre detection optics give the sensitivity and stability required for absolute molecular weight measurement.

Applications:

 
Need help or have a question? +1-858-558-2599
 

Need help or have a question?

+1-858-558-2599
EMEA UK:
+44 161 721 5247