LCMS Validated Assays List

Intertek Pharmaceutical Services has developed a list of validated LC-MS generic assays.

The following list of validated non-proprietary Liquid Chromatography - Mass Spectrometry (LC-MS/MS) assays are available for your review. Please contact us if you would like to discuss these services further or if you would like to discuss the development and validation of LC-MS bioanalytical assays for other compounds.

Compound(s)SpeciesMatrixAnticoagulantAssay Range
AcetaminophenHumanPlasmaK2EDTA50-30,000 ng/mL
AldosteroneHumanUrineNA0.5-100ng/mL
Aldosterone/11-deoxycortisolHumanPlasmaK2EDTA10-2500pg/mL
Atorvastatin / MetabolitesHumanPlasmaK2EDTA0.05-50 ng/mL
Cortisol/CorticosteroneHumanPlasmaK2EDTA10-500ng/mL / 0.5-25ng/mL
Cyclosporin AHumanWhole BloodEDTA0.1-100ng/ml
DexamethasoneHumanPlasmaK2EDTA2-500ng/ml
DocetaxelHumanPlasmaNaHep1-1000ng/ml
DoxorubicinHumanPlasmaK3EDTA5-1000ng/ml
Dronedarone / DebutyldronedaroneHumanPlasmaK2EDTA0.5-250ng/ml
DrospirenoneHumanPlasmaK2EDTA2-1000ng/ml
Ethinyl EstradiolHumanPlasmaK2EDTA2.5-500pg/ml
Gemcitabine / dFdUHumanPlasmaNaHep5-1000ng/ml
Itraconazole/ HydroxyitraconazoleHumanPlasmaK2EDTA1-500ng/ml / 2-1000ng
Irinotecan/SN-38HumanPlasmaK2EDTA1-500ng/mL / 0.5-250ng/mL
Lidocaine / MEGXHumanPlasmaK2EDTA1-500ng/ml
LinezolidHumanPlasmaK2EDTA0.05-20µg/mL
MetforminHumanPlasmaK2EDTA10-2500ng/mL
MethotrexateHumanPlasmaK2EDTA0.5-500ng/ml
OmeprazoleHumanPlasmaNaHep1-1000ng/ml
PaclitaxelHumanPlasmaNaHep1-500ng/ml
PaclitaxelHumanWhole BloodK3EDTA5-1000ng/ml
RanolazineHumanPlasmaNaHep50-10000ng/ml
Simvastatin / Simvastatin AcidHumanPlasmaK2EDTA0.2-25ng/ml
VancomycinHumanPlasmaK2EDTA10-5000ng/mL
VinorelbineHumanPlasmaNaHep0.2-25ng/ml
(R)-Warfarin & (S)-WarfarinHumanPlasmaK2EDTA2-400ng/ml
 
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