Ocular Tissue Bioanalysis

Ocular tissue LC-MS/MS bioanalysis laboratory services supporting ocular drugs preclinical or clinical development

Intertek's ocular tissue LC-MS/MS bioanalysis experience extends over a decade in regard to development and highly optimised validation for a wide variety of compounds in multiple ocular matrices of different species which adhere closely to regulated bioanalysis guidance.

A diverse platform of homogenization and extraction techniques is available for processing ocular tissues and fluids to ensure optimal recovery of analytes. Technologies such as multi-tube bead homogenization and high energy ultrasonication are often employed individually, or in conjunction with more traditional processing techniques.

Non-GLP studies are also routinely conducted to support discovery, lead optimization and proof of concept programs of ocular drugs.

Methods have been validated in the following ocular matrices:

  • Aqueous humor
  • Vitreous humor
  • Retina
  • Choroid
  • Sclera
  • Cornea
  • Iris ciliary body
  • Lens
  • Lacrimal gland
  • Trabecular meshwork
  • Eye lid
  • Tears
  • Conjunctiva
  • Iris
 
Need help or have a question? +1-858-558-2599
 

Need help or have a question?

+1-858-558-2599
EMEA UK:
+44 161 721 5247