Bioanalytical and Protein LCMS Facilities and Equipment

High capacity LC-MS bioanalysis / protein analysis services for rapid sample analysis and turnaround for all phases of discovery & drug development supporting your global studies

Bioanalytical Liquid Chromatography-Mass Spectrometry (LC-MS) Laboratory Resources

Our bioanalytical and protein LC-MS facilities and equipment form a key component of our custom-designed bioanalytical center of excellence located in San Diego, California, USA. The site includes laboratory space for data production and analysis, quality control personnel and offices. The San Diego center conducts GLP-compliant and non-GLP studies. Additionally, immunochemistry and cell imaging services are offered in San Diego.

Our LC-MS technologies include modern mass spectrometry instrumentation, a segregated sample login area dedicated to the receipt and unpacking of biological samples, a comprehensive Rees Scientific e-Centron™ temperature monitoring system with an alarm system for all freezers, refrigerators and selected ambient zones, a diesel powered generator, and uninterrupted power supplies providing automated power backup. 

Additionally, we house a restricted access fireproof archive and server rooms with constant temperature and environmental controls.

Bioanalytical and Protein LC-MS Equipment

• SCIEX API 5000 with TurboIonSpray and Heated Nebulizer (3)
• SCIEX API 4000 with TurboIonspray and Heated Nebulizer (8)
• SCIEX API 3000 with TurboIonspray and Heated Nebulizer (2)
• SCIEX API 6500 with TurboIonspray and Heated Nebulizer (2)
• Shimadzu SCL-10A and SCL-20AD Controllers (15)
• Shimadzu LC-10AD and LC-20AD XR HPLC Pumps (27)
• HTS PAL Autoinjectors (Leap Technology) (15)
• Thermo Q Exactive Plus Biopharma with HESI II and easy nano sources
• Thermo / Dionex U3000 RSLC nano, capillary and microflow UHPLC, autosampler
• Tomtec Quadra 96 Semi-Automated SPE System (4)
• Hamilton StarLET Robotic Pipetting System (1)
• Cohesive Aria TX-2 TurboFlow HTLC System (1)
• Zymark TurboVap LV Evaporator (6)
• Biotage SPE dry™ 96 Evaporator (3)
• Mettler Toledo MT5 Balance (6 place) (2); MTXS 204 (4 place); MT Adventurer SL, Ohaus SP2001 balance
• Sorvall Legend RT+ temperature controlled Centrifuge (2) and Legend XTR temperature controlled centrifuge
• Eppendorf 5417C Centrifuge; 5430 and 5415R (both temperature controlled) 
• Chemical safety fume hoods (10)
• Labconco Purifier® Class I safety enclosure (6)
• Omni Bead Ruptor homogenizer (2)
• Branson 3800 and 3510 water bath sonicators (3)
• Thermo precision water bath (1) and shaking precision water bath (2)
• Vortex Genie vortexer (11)
• VWR Multi-Tube Vortexer (4)
• (88) -70/80°C freezers
• (23) -20°C freezers
• Rees Scientific e-Centron temperature monitoring and alarm system (1)