Efficacy of Preservation of Cosmetics

Preservatives are necessary to ensure consumer protection and prevention of cosmetics spoilage during normal and reasonably foreseeable product use.

Selection of preservatives requires in situ determination of their efficacy by microbiological challenge tests, which should be carried out by an expert, and include representative bacteria, yeast and mould that may be pathogenic, or may cause spoilage. Common test methods include USP Chapter <51>, BP Appendix XVIC, EP Chapters 5.1.3 and CTFA’s Microbiology Guidelines. Acceptance criteria were usually taken from that of the pharmacopoeia or CTFA.

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