In vitro cleaning evaluation of toothbrushes, interdental brushes, flosses and tapes through in vitro and instrumental efficacy studies
In vitro cleaning efficacy studies allow the evaluation of toothbrushes, interdental brushes, flosses and tapes which have been developed to remove stain or plaque from tooth surfaces and interproximal spaces.
New toothbrushes and interdental cleaning products are constantly being developed with novel materials, different filament types / profiles, or penetration enhancers. Such products may have been developed to improve plaque or stain removal from difficult to reach places. Independent evidence for improvement is subsequently sought to support pack claims or direct further development.
Our team of laboratory scientists are able to carry out comparative testing for the cleaning evaluation of brushes, flosses and tapes. We are experienced in the design and fabrication of dental and interproximal cleaning models using extracted human teeth which can either be stained or coated with an artificial plaque. Following use of the product, cleaning efficacy is assessed using digital image analysis giving you a robust insight into cleaning efficacy.
Cleaning studies are appropriately powered to investigate significant improvements in efficacy and sufficient repeats are planned to assess product and assessor variability. Images can be assessed subjectively or by using digital analysis. Percentage cleaning data and any requested statistical analysis is provided in a report containing tables, graphs and images.
For over 18 years our Clinical Research Services group has been a trusted partner for developers and manufacturers of oral care products. We provide a one source solution for both in vitro studies and human trials providing robust data to support the efficacy and safety of novel treatments.