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Cleaning evaluation of toothbrushes, interdental brushes, flosses and tapes

In vitro cleaning evaluation of toothbrushes, interdental brushes, flosses and tapes through in vitro and instrumental efficacy studies

In vitro cleaning efficacy studies allow the evaluation of toothbrushes, interdental brushes, flosses and tapes which have been developed to remove stain or plaque from tooth surfaces and interproximal spaces.

New toothbrushes and interdental cleaning products are constantly being developed with novel materials, different filament types / profiles, or penetration enhancers. Such products may have been developed to improve plaque or stain removal from difficult to reach places. Independent evidence for improvement is subsequently sought to support pack claims or direct further development.

Our team of laboratory scientists are able to carry out comparative testing for the cleaning evaluation of brushes, flosses and tapes. We are experienced in the design and fabrication of dental and interproximal cleaning models using extracted human teeth which can either be stained or coated with an artificial plaque. Following use of the product, cleaning efficacy is assessed using digital image analysis giving you a robust insight into cleaning efficacy.

Cleaning studies are appropriately powered to investigate significant improvements in efficacy and sufficient repeats are planned to assess product and assessor variability. Images can be assessed subjectively or by using digital analysis. Percentage cleaning data and any requested statistical analysis is provided in a report containing tables, graphs and images.

For over 18 years our Clinical Research Services group has been a trusted partner for developers and manufacturers of oral care products. We provide a one source solution for both in vitro studies and human trials providing robust data to support the efficacy and safety of novel treatments.

 
Intertek Clinical Research Services (CRS) has a dedicated in vitro laboratory which conducts testing of all aspects of Oral Care products. We are particularly adept in designing bespoke in vitro models to cater for your specific requirements. Intertek Clinical Research Services is licensed to handle and store human tissue under the Human Tissue Act 2004 and follows the principles outlined within the act as well as complying with local ethical guidelines.
Our team of laboratory scientists have a combined experience of over 30 years of testing oral care products and between them have degrees/PhD/MSc in Dentistry, Chemistry, Analytical Chemistry and Biological Sciences. They have also contributed to a variety of scientific papers in collaboration with many well-known clients and have presented posters at International scientific conferences.
 

Oral care product trial services:

Need help or have a question? +44 (0) 151 347 4810
 

Need help or have a question?

+44 (0) 151 347 4810
Wirral (UK):
+44 (0) 151 347 4810