Clinical Research Services

4-Front Research 

Unit 6
Capenhurst Technology Park,
Capenhurst Lane
Chester
Cheshire, CH1 6EH
United Kingdom

With offices in Chester, Manchester, Maldon and Paris

 

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Dermal Safety Studies

Dermal Consumer Product safety studies and tests.

Intertek offers dermal safety studies with a variety of standard methods to confirm the safety of your skincare products during and after development. Intertek 4-Front has a wealth of experience in safety evaluations. 

Dermal Safety Study types include:

Primary Irritation studies 

  •  24, 48, 72 or 96-hour patch tests to screen for irritation potential. 
Cumulative Irritation
  •  14 or 21-day patch test to investigate potential irritation from chronic exposure. 
Repeat Insult Patch Tests: Sensitisation
  •  100 or 200 subject patch test to investigate sensitisation (allergy) potential following repeated exposures & a challenge at a naïve site 
Phototoxicity and Photosensitisation Screening tests
  •  Screening test for irritancy and/or allergy potential following exposures to UV light 
Comedogenicity Screening tests
  • Comedogenicity screening test for potential of a product to promote the formation of comedones (“blackheads”) following chronic exposure 
Soap Chamber tests
  •  Benchmarking test for mild surfactant products, based on the Frosch & Kligman method 
Normal In-Use Safety studies
  •  Provides reassurance that products do not cause adverse reactions under normal use conditions. 
Ocular Irritation tests
  •  Products are applied around or directly into the eyes, under the supervision of Ophthalmologist. 
Exaggerated Use Conditions
  •  Provides reassurance that products do not cause adverse reactions, under most use conditions. 

The Intertek 4-Front volunteer database can provide standard, or more sensitive, volunteers to suit your specific requirements.

to see how Intertek can help your organization with Dermal Safety Studies.